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PharmD.Hadeel on Instagram‎: "⁨ Febuxostat هو مثبّط انتقائي لـ Xanthine oxidase يمنع تحويل hypoxanthine → xanthine → uric acid في مسار تحليل البيورينات → يقلل إنتاج حمض اليوريك. متى ممكن نفكر نختار Febuxostat بدلاً من Allopurinol؟ •المرضى الذين لم يستجيبوا لجرعة قصوى مضبوطة من Allopurinol. •المرضى الذين لديهم عدم تحمّل أو تحسس من Allopurinol. •الحالات التي يكون فيها Allopurinol غير مناسب طبياً ‏(Boxed Warning) — مخاطر القلب / الوفاة استخدام Febuxostat ارتبط بزيادة خطر الوفاة القلبية مقارنة بالعل
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