The ubiquitin-editing enzyme A20 is a critical negative regulator of inflammation and cytokine-mediated activation of the transcription factor NF-κB; however, little is known about the mechanisms of ...

Itching is among the most persistent of skin sensations, requiring an immediate response. However, scientists say it is a protective sensation that stimulates the individual to eliminate parasites and ...

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Chronic itching, or pruritis, appears to involve more than the usual itch signals. Instead, it seems that chronic itching results when pain signals become involved, intensifying the itch sensation.