The single-handedness of biological molecules is critical for molecular recognition and replication processes and would seem to be a prerequisite for the origin of life. A drawback of recently ...
In chemistry, breaking a mirror isn’t always a harbinger of bad luck. Using a trio of catalysts and some blue light, researchers have transformed a racemic mixture of mirror-image molecules into a ...
Making carbon–carbon bonds is hard. Linking racemic mixtures of two alkyls while simultaneously controlling the stereochemistry of both ends of the product is nigh on impossible. Now Gregory Fu, ...
From 2001 to 2011, the US Food and Drug Administration approved 9 single-enantiomer drugs with racemic precursors. None showed pre-approval evidence of improved efficacy over the racemic precursor. We ...
Some research shows a new drug called ketamine is effective in the treatment of depression. Ketamine is available in two forms: Esketamine and racemic ketamine. Racemic ketamine (used in ketamine ...
The racemic compound (R, S)-(±)-ibuprofen is a popular and well understood active pharmaceutical ingredient, but it has several disadvantageous formulation properties such as poor solubility, low ...
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