Figure 1: Myosin (Myo) IIA and myosin IIB localize to apical epithelial junctions. Figure 2: Differential regulation of myosin IIA and myosin IIB localization at apical junctions. Figure 4: Homophilic ...

During migration in tissue in vivo or in culture in a three-dimensional (3D) extracellular matrix (ECM), endothelial cells, fibroblasts and tumour cells exhibit a characteristic complex shape that ...

In a decades-long effort, researchers have discovered how to tweak the molecular pathways that turn heart muscle motors up or down ...

The novel cardiac myosin inhibitor aficamten improved peak oxygen uptake in symptomatic obstructive hypertrophic cardiomyopathy (HCM), the pivotal SEQUOIA-HCM trial showed. At 24 weeks, the mean ...

Boron, though required only in minimal amounts, is vital for plant development. It strengthens cell walls and supports the growth of roots and shoots. Normally, boron, in the form of boric acid, is ...

In its early stages, Alzheimer disease is increasingly recognized as a disease of synapses, those key mediators of memory storage in the brain. Enhancing synaptic function, therefore, might be a ...

JUPITER, Fla., Feb. 26, 2025 /PRNewswire/ -- Myosin Therapeutics, Inc., a biotechnology company developing novel therapies for cancer and neurological disorders, has closed its second seed funding ...

A decade ago, when Courtney Miller of Scripps Research in Florida found that blocking a specific protein can interrupt methamphetamine addiction in mice, it was difficult to imagine drugs targeting ...

"HCM is a heart muscle disease associated with a significant symptom burden. This approval of a new drug, Myqorzo, represents a meaningful addition to the treatment options available for symptomatic ...

A viral animation shows a myosin molecule transporting endorphins, which can be thought of as a visual representation of the feeling of happiness. Since at least 2014, one of the Internet's most viral ...