A two-headed molecule designed by Stanford Medicine researchers hijacks one of the most common protein drivers of B-cell ...

Imagine tiny machines, smaller than a virus, spinning inside cancer cells and rewiring their behavior from within. No surgery, no harsh chemicals, just precision at the molecular level. Two ...

Cells are regularly faced with environmental stresses that may damage or destroy them. To survive, they quickly adjust their gene expression to protect themselves. This is especially true for cancer ...

Peter Mac researchers have identified potential new drug targets for pancreatic cancer by uncovering proteins cancer cells ...

Molecular diagnostics are specialized tests doctors use to look at proteins, RNA, and DNA in and on cancer cells. When you have breast cancer, they show your doctors what’s unique about your tumor so ...

Cancer drugs are designed to shut tumors down. But sometimes, in the very act of attacking a tumor, treatment can also help a small fraction of cancer cells become harder to kill. A new study from ...

Molecular glues are small, monovalent molecules that reshape an E3 ubiquitin ligase (E3) surface to promote a new protein-protein interaction with a target, triggering ubiquitination and removal by ...

Three Versus 6 Months of Adjuvant Oxaliplatin-Fluoropyrimidine Chemotherapy for Colorectal Cancer: Final Results of SCOT—An International, Randomized, Phase III, Noninferiority Trial Overall, 210 ...

4C Biomed’s article introduces its Anti-4CB1, a fully human monoclonal antibody against HVEM (Herpes Virus Entry Mediator, or TNFRSF14), a novel immune checkpoint which is highly expressed in ...

Chemosensitivity — the degree to which cancer cells respond to therapeutic agents — remains one of the central determinants of treatment success in ...