Clonal hematopoiesis of indeterminate potential (CHIP) is an age-related condition associated with increased mortality among patients with cancer. CHIP mutations with high variant-allele frequencies ...
Across treatment classes, CH associated with increased therapy-related cytopenias, particularly neutropenia, and DNMT3A/TET2 ...
New insights reveal how hidden genetic mutations could be silently fueling heart disease in middle-aged adults, paving the way for personalized prevention strategies. In a recent study published in ...
In a recent study published in the journal Nature Genetics, a team of researchers from the United Kingdom (U.K.) and the United States (U.S.) analyzed whole blood samples from a large cohort of U.K.
Results from METIS (EF-25), an international, multicenter phase III randomized study evaluating the efficacy and safety of tumor treating fields (TTFields) therapy in NSCLC patients with brain ...
Effect of indoximod-based chemo-immunotherapy in patients with pediatric brain tumors on activation and clonal proliferation of a circulating population of early non-exhausted stem-like CD8+ T cells ...
BOSTON – A new clinical tool developed by a team of researchers led by the Dana-Farber Cancer Institute pinpoints which Clonal hematopoiesis patients are at highest risk for cancer progression. Their ...
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