This is a preview. Log in through your library . Abstract ATP is the universal energy currency of living cells, and the majority of it is synthesized by the F1 F0 ATP synthase. Inhibitors of this ...

Osteoblasts derived from MSCs are cells required for bone formation. Oxidative phosphorylation produces a lot of ATP and other products including NAD+ and ROS. These factors play important roles in ...

Inside your cells, mitochondria keep you alive by turning food into usable energy. Researchers from the University of Technology Sydney and Memorial University of Newfoundland are now exploring how to ...

TMC207 is a first-in-class anti-TB diarylquinoline (also named R207910 or the 'J' compound) with activity against drug-sensitive and drug-resistant TB. TMC207 inhibits the proton pump of mycobacterial ...

A common food additive that gives M&Ms and Gatorade their blue tint may offer promise for preventing the additional -- and serious -- secondary damage that immediately follows a traumatic injury to ...

New Assay Chemistry Can Identify the Type of Mechanistic Toxicity and Help Reduce Drug Failures Mitochondria are responsible for the production of >90% of mammalian cell energy and are intimately ...

Early tests of a novel compound in mice with glaucoma should come as welcome news to millions of people around the world now suffering with this leading cause of vision loss. Researchers have shown ...

Aromatic compounds are common growth substrates for microorganisms and are also prominent environmental pollutants. The crucial step in their degradation is to overcome the huge resonance energy that ...